Elevated Neutrophil-Lymphocyte Ratio in Malignant Laryngeal Lesions
نویسندگان
چکیده
Laryngeal squamous cell carcinomas (LSCC) are the most frequently seen cancers among head and neck squamous cell carcinomas (HNSCC), and they constitute 1-2% of all malignancies worldwide (Sadri et al., 2006). Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. LSCC develops as a result of structural and cytological alterations in the laryngeal squamous epithelium (Marcos et al., 2011). Transformation of precancerous laryngeal lesions (PLL), which include various degrees of dysplasia and carcinoma in situ (CIS), to invasive cancer is not infrequent (Ferlito et al., 2012). Currently, there is no sufficient evidence for the use of biomarkers in predicting the future behavior of laryngeal dysplastic lesions in the clinical practice (Nankivell et al., 2011). Despite extensive research, reliable markers with
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